The term photosynthesis is usually only thought of in plant life. What many fail to understand is that we photosynthesize. The sun’s energy is required to promote the photosynthesis of vitamin D3 in the skin for enhancing the efficiency of intestinal calcium absorption.
Plants don’t make vitamin D3. Only animals and humans can do that. Cholesterol in the form of pre-vitamin D is converted into cholecalciferol in our skin, which is then converted into Calcidiol in our liver, then into Calcitriol primarily in the kidneys and some in other cells.
Calcidiol is the storage form of vitamin D. Calcitriol is the most potent active form of vitamin D, and one of the most potent chemicals in the body. This form of vitamin D has potent anticancer properties.
Ergosterol is a plant and fungal sterol. This is what ergocalciferol or vitamin D2 is made from. It’s not effective as vitamin D for humans or animals. Humans and animals synthesize cholesterol into vitamin D3 (cholecalciferol), in relatively large quantities in the skin. During exposure to sunlight, the cholesterol in the epidermal and dermal cells absorb ultraviolet B (UVB) radiation. The absorption of this radiation results in converting cholesterol into the vitamin D3 structure. Sunscreens efficiently absorb UVB radiation and thus markedly diminish the total number of UVB photons that reach the cholesterol in the skin’s cells.
Glass effectively filters out UVB rays, reducing vitamin D levels. Our lifestyles have added to the deficiencies. Our kids don’t play outside like before, they’re more attached to electronics. We hide from the sun and smear ourselves with sun screen. This has set in motion many serious diseases. There’s more cancer in the northern latitudes with less sun.
Vitamin D deficiency in adults sets up secondary hyperparathyroidism, precipitating and exacerbating osteoporosis. This secondary hyperparathyroidism may show normal serum calcium levels while upsetting the balance between calcium and phosphorus. This results in demineralization of the bone, and osteomalacia. Because a non mineralized matrix can’t provide structural support, the risk of fracture is increased.
Melanin, a natural sunscreen protects humans from blistering solar radiation. This has been an adaptation in equatorial regions of the world. This skin pigment is an extremely effective sunscreen with absorption properties from the ultraviolet C and competes with pre-vitamin D for UVB photons. Thus, people of color with greater amounts of melanin in their epidermis are less efficient in producing vitamin D3. Because of this, it’s more important for those with darker skin in the northern latitudes to take an oral vitamin D3 supplement.
Most tissues and cells in the body, including heart, stomach, pancreas, brain, skin, gonads, and activated T and B lymphocytes, have nuclear receptors for the active form of D3. Because of the presence of these widespread receptors, it’s not surprising to see that D3 has a multitude of biologic effects which aren’t related just to bone structure.
Vitamin D3 down-regulates hyper-proliferative cell growth. Normal and cancer cells which have vitamin D receptors often respond by decreasing their proliferation and enhancing their maturation. Here’s the rationale for using it to treat psoriasis and cancers.
The most common autoimmune diseases, including type 1 diabetes, rheumatoid arthritis, and multiple sclerosis, have all been successfully prevented in models using mice that were prone to these diseases if they received D3 early in life.
Hiding from the sun isn’t the answer. That big red ball in the sky is our lifeline. Without it, we would perish. The use of proper nutrition to direct calcium into your cells is the answer. Vitamin D needs to be paired with natural vitamin C, Vitamin F, and Ionized Calcium Lactate to truly be effective. See the next blog on these.